Nexera XS (40-Series) UHPLC System

Experience New Benchmarks of Intelligence, Efficiency, and Design.

Nexera XS excels at fast separations, easily handling small ID UHPLC columns with sub-2 micron particles or the popular SPP phases for high efficiency and lower back pressure. A common XS configuration may have a 4-channel solvent selection valve on each pump providing versatility for method development. Five to ten minute run times are the norm.

Utilizing Analytical Intelligence (AI) technologies, and featuring the most advanced performance features available, the New Nexera XS will transform your workflows for maximum reliability, uptime, and efficiency.

Download Brochure

Key Features

Analytical Intelligence

New Smart Flow control during start-up and shutdown
Auto-diagnosis and Auto-recovery from flow anomalies
Remote maintenance and laboratory management
Mobile Phase Monitor with true gravimetric monitoring of the available mobile phase quantity (Optional)


High efficiency chromatography with 105 MPa (~15,000 psi) pressure tolerance and LPGE or HPGE solvent delivery

Speed and Carryover

Ultra-fast injection cycles (7 sec) with lowest carryover


Connection via Ethernet


High capacity sample handling with optional plate changer. Remarkably small footprint.