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LC-MS/MS Method Validation for Forensic Toxicology Labs
In forensic toxicology, LC-MS/MS has become the gold standard for detecting and quantifying compounds, particularly in urine analysis. With over 20 years of expertise, ZefSci provides tailored LC-MS/MS method validation solutions for testing specific compounds in urine, including optimized mass spectrometry parameters for each compound and fast HPLC methods.
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LC-MS/MS Method Validation Service for Urine Testing
At ZefSci, we meticulously validate each developed method according to industry best practices and regulatory guidelines to guarantee accuracy, precision and reliability of your urine analysis results.
Our LC-MS/MS validation services encompass a range of critical indicators, including:
- LODs and LOQs
- Linearity
- Accuracy
- Precision
- Specificity
- Carryover
- Matrix effect
- Matrix interference
- Internal standard interference
- Ion suppression/Enhancement
- Analyte/Urine stability
- Ion ratios
- Retention times
Method Validation for 100 Forensic Compounds
Optimize and validate the analysis of 100 forensic compounds comprising 60 drugs and 40 internal standards in urine using LC-MS/MS.
Forensic Panel List
Our forensic panel includes a comprehensive list of compounds commonly analyzed in urine testing.
- 6-MAM
- 7-Aminoclonazepam
- 7-hydroxymitragynine
- 9-hydroxyrisperidone
- Alpha-Hydroxyalprazolam
- Alpha-Hydroxymidazolam
- Alprazolam
- Amitriptyline
- Amphetamine
- Aripriprazole
- Benzoylecgonine
- Buprenorphine
- Carisoprodol
- Citalopram
- Clonazepam
- Codeine
- Cotinine
- Desipramine
- Desmethylvenlafaxine
- Dextromethorphan
- Doxepin
- EDDP
- Fentanyl
- Fluoxetine
- Gabapentin
- Haloperidol
- Hydrocodone
- Hydromorphone
- Hydroxybupropion
- Ketamine
- Lorazepam
- MDMA
- Meperidine
- Meprobamate
- Methadone
- Methamphetamine
- Mitragynine
- Morphine
- Naloxone
- Naltrexone
- Norbuprenorphine
- Nordiazepam
- Norfentanyl
- Norketamine
- Noroxycodone
- Nortriptyline
- Oxazepam
- Oxycodone
- Oxymorphone
- Paroxetine
- PCP
- Quetiapine
- Risperidone
- Tapentadol
- Temazepam
- THCA
- Tramadol
- Trazodone
- Venlafaxine
- Ziprasidone
Internal Standards List
ZefSci’s internal standards list includes isotopically labeled compounds designed to enhance the accuracy, precision and reliability of urine analyses.
- 6-MAM-d6
- 7-Aminoclonazepam-d4
- 7-hydroxymitragynine-d3
- 9-hydroxyrisperidone-d4
- Alprazolam-d5
- Amphetamine-d5
- Aripriprazole-d8
- Benzoylecgonine-d8
- Buprenorphine-d4
- Citalopram-d6
- Codeine-d6
- Cotinine-d3
- Desipramine-d3
- Fentanyl-d5
- Gabapentin 13C3
- Haloperidol-d4
- Hydrocodone-d6
- Hydromorphone-d6
- Hydroxybupropion-d6
- Ketamine-d4
- Meperidine-d4
- Meprobamate-13C3
- Methadone-d9
- Methamphetamine-d5
- Morphine-d6
- Norbuprenorphine-d3
- Nordiazepam-d5
- Norketamine-d4
- Oxycodone-d6
- Oxymorphone-d3
- PCP-d5
- Quetiapine-d8
- Risperidone-d4
- Tapentadol-d3
- Temazepam-d5
- THCA-d3
- Tramadol-13CD3
- Trazodone-d6
- Venlafaxine-d6
- Ziprasidone-d8
Optimize Your Existing LC-MS/MS Method
If you already have an LC-MS/MS method for drug panel analysis in urine samples, partner with ZefSci to enhance your approach and achieve reliable results. Our team will fine-tune your method for peak performance by resolving urine sample variability to eliminate false positives and negatives.
ZefSci…. The Way LCMS Service Should Always Be
Discover the new standard in analytical instrument service with ZefSci multivendor LCMS maintenance. Call 1-866-854-7988 now for rapid repair or get an instant service quote today.
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