
High-Sensitivity & High-Speed Scanning at 30,000 u/sec
Enhancements in chromatography and sub-2 micron columns have resulted in narrower peak widths, thereby increasing resolution. Analysts are demanding shorter chromatographic run times while adding more analyses to a single method. With these two factors at play, it is clear that the LCMS-8050’s ultra-fast mass spectrometer can accurately and reliably detect each compound in a sample.
The LCMS-8050 is capable of simultaneously obtaining both qualitative and quantitative information in a single analysis. Rapid acquisition allows MS/MS scans and MRM measurements to be performed concurrently while maintaining quantitative accuracy. MS/MS scans are usable and reliable because even at 30,000 u/sec, Shimadzu uses a 0.1 u scan step.
Download Brochure Download SpecificationsKey Features
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Unmatched Speed & Sensitivity
Simultaneous Collection of Multiple MRM Events With Full Scan Product Ion Spectra at Different Collision Energies
Fast Polarity Switching
- Uses UF Technologies to switch polarity in 5 ms
Detection
- Fast cycle time helps to detect more compounds with greater confidence and precision
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Technology
- UF-Qarray: The innovative design of the Qarray allows for enhancement of ion signal while simultaneously reducing noise. This yields ultra-low detection limits, allowing for trace quantitation
Easy Operation/Maintenance
- Quickly and easily replace the DL without breaking vacuum, providing greater uptime and usability
Newly Designed Ionization Unit
- No cable or tubes and no tools are needed to detach the needles fitted in APCI and DUIS units
Specifications
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Model
- LCMS-8050
Mass Range
- m/z 2 to 2,000
Sensitivity
- ESI positive:
1 pg reserpine, S/N > 250,000:1 (RMS) - ESI negative:
1 pg chloramphenicol, S/N > 250,000:1 (RMS)
Resolution
- R < 0.7 u FWHM
Cross-talk
- < 0.003 %
Minimum Pause Time
- 1 msec
Minimum Dwell Time
- 0.8 msec
Scan Speed
- Max 30,000 u/sec (in all modes of scanning)
(0.1 u step: 300,000 data points/sec)
Block heater Maximum Temperature
- ESI/DUIS: 500 °C
- APCI: 300 °C
Interface Maximum Settable Temperature
- ESI/DUIS: 400 °C
- APCI: 500 ° C
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Mass Stability
- 0.1 u / 24 hr
Mass Accuracy
- ±0.15 u or less (m/z 1,000)
Polarity Switching Time
- 5 msec
Interface
- ESI (Standard)
- APCI (Optional), DUIS (Optional)
Applicable LC Flow Rate
- ESI 1 μL/min to 2 mL/min
MRM Transition Speed
- Max 555 channels/sec
DL Maximum Temperature
- 300 °C
Analysis Mode
- 1 Scan/SIM
- Q3 Scan/SIM
MRM - Precursor ion scan
- Product ion scan
- Neutral loss scan
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