8040 – LC-MS/MS

LCMS-8040 Triple Quadrupole Liquid Chromatograph Mass Spectrometer (LC-MS/MS)

Consumer demand for higher quality products has led to the implementation of stricter government regulations and oversight in order to ensure safety and product conformity. The food safety community is just one sector requiring lower minimum residue levels with greater testing frequency for a broader number of compounds. The triple quad LCMS-8040 has stepped up to the challenges of high-throughput sensitive routine analysis. As shown, the LCMS-8040 can analyze a 226 pesticide mixture in less than two minutes, making it an ideal instrument for meeting a laboratory’s demanding requirements.

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Mass range
m/z 2 to 2,000
ESI positive:
1 pg reserpine, S/N>30,000:1 (RMS)
ESI negative:
1 pg chloramphenicol, S/N>30,000:1 (RMS)
R < 0.7 u FWHM
Mass stability
0.05 u / 12 hr
Cross talk
< 0.003%
Minimum pause time
1 msec
Minimum dwell time
0.8 msec
Scan speed
Max 15,000 u/sec
(0.1 u step: 150,000 data points/sec)
Polarity switching time
15 msec
ESI (Standard),
APCI (Optional), DUIS (Optional)
Applicable LC ow rate
ESI 1 μL/min to 2 mL/min
MRM transition speed
Max 555 channels/sec
DL maximum temperature
300 °C
Block heater maximum temperature
ESI/DUIS: 500 °C
APCI: 300 °C
Interface maximum temperature
APCI: 500ºC
Analysis mode
Q1 Scan/SIM
Q3 Scan/SIM
Precursor ion scan
Product ion scan
Neutral loss scan
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Features & Benefits

Ultra-High Sensitivity

  • Newly improved ion optics and collision cell technology
  • Higher multiple reaction monitoring (MRM) sensitivity
  • A five-fold increase in sensitivity (reserpine, S/N ratio)
  • Higher sensitivity for scan mode measurements, expanding the potential range of LC/MS/MS applications.

Ultra-High Speed

  • Higher sensitivity while maintaining the high speed offered by the LCMS-8030
  • Ultrafast MRM transition speeds — up to 555 MRMs per second
  • Features polarity switching at 15 ms, dramatically improving throughput.

Ultra-High Reliability

  • MRM optimization takes only minutes to perform.
  • Multiple compounds can be optimized in an unattended sequence, freeing the analyst from tedious work.
  • MRM parameters optimized for the LCMS-8030 can be transferred to the LCMS-8040
  • As easy to maintain as the LCMS 8030
  • Interchangeable consumables